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• Activity deltas table
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Motif ID: NFY{A,B,C}.p2

Z-value: 6.354

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_91926109	194.367	NM_001827	CKS2	CDC28 protein kinase regulatory subunit 2
chr14_+_54863672	159.261	NM_001130851 NM_005192	CDKN3	cyclin-dependent kinase inhibitor 3
chr1_-_197115566	143.977	NM_001206846 NM_018136	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr17_-_38574042	142.957	NM_001067	TOP2A	topoisomerase (DNA) II alpha 170kDa
chr4_-_174255454	139.247	NM_001130688 NM_002129	HMGB2	high mobility group box 2
chr2_+_10262853	129.632	NM_001034	RRM2	ribonucleotide reductase M2
chr1_-_153643456	127.508		ILF2	interleukin enhancer binding factor 2, 45kDa
chr1_-_153643433	116.836		ILF2	interleukin enhancer binding factor 2, 45kDa
chr1_-_153643417	115.330		ILF2	interleukin enhancer binding factor 2, 45kDa
chr5_+_68462948	113.383		CCNB1	cyclin B1
chr1_-_153643428	111.296		ILF2	interleukin enhancer binding factor 2, 45kDa
chr2_+_10262694	111.171	NM_001165931	RRM2	ribonucleotide reductase M2
chr19_-_55919324	109.834	NM_014501	UBE2S	ubiquitin-conjugating enzyme E2S
chr20_+_47662782	108.484	NM_001316	CSE1L	CSE1 chromosome segregation 1-like (yeast)
chr5_+_177631496	106.039	NM_004499 NM_031266	HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B
chr5_+_68462985	105.158		CCNB1	cyclin B1
chr14_+_58711599	104.525		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr2_-_61765394	103.742	NM_003400	XPO1	exportin 1 (CRM1 homolog, yeast)
chr1_+_154947166	103.633		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr5_+_177631533	102.484		HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B
chr15_+_41624891	102.040	NM_001243142 NM_001243143 NM_001243144 NM_016359 NM_018454	NUSAP1	nucleolar and spindle associated protein 1
chr1_+_154947147	101.303		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr17_-_79818370	101.084		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr17_+_26646120	100.517	NM_014573	TMEM97	transmembrane protein 97
chr11_+_63953630	99.793		STIP1	stress-induced-phosphoprotein 1
chr14_+_58711555	98.461		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr19_-_55918980	98.375		UBE2S	ubiquitin-conjugating enzyme E2S
chr1_+_154947116	95.497	NM_001826	CKS1B	CDC28 protein kinase regulatory subunit 1B
chr5_+_177631534	95.346		HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B
chr17_-_79818318	93.701		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr1_+_43148096	92.860		YBX1	Y box binding protein 1
chr17_-_76183074	92.331	NM_003258	TK1	thymidine kinase 1, soluble
chr15_+_41625052	91.794		NUSAP1	nucleolar and spindle associated protein 1
chr20_+_30326903	91.317	NM_012112	TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)
chr10_+_62538250	89.698		CDK1	cyclin-dependent kinase 1
chr15_+_59397276	88.266	NM_004701	CCNB2	cyclin B2
chr17_+_6347733	87.047	NM_001195228 NM_019013	FAM64A	family with sequence similarity 64, member A
chr3_+_179280686	86.538	NM_004301 NM_177989 NM_178042	ACTL6A	actin-like 6A
chr17_-_79818418	86.308		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr17_+_45727274	84.800	NM_002265	KPNB1	karyopherin (importin) beta 1
chr1_+_110881944	84.424	NM_001201545 NM_022768	RBM15	RNA binding motif protein 15
chr1_+_43824598	83.822	NM_001255	CDC20	cell division cycle 20 homolog (S. cerevisiae)
chr1_-_28241233	83.616	NM_002946	RPA2	replication protein A2, 32kDa
chr1_-_225615787	83.556	NM_002296	LBR	lamin B receptor
chr9_-_128003634	83.229	NM_005347	HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr10_+_62538088	81.118	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr14_+_58711457	81.118	NM_002788 NM_152132	PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr10_+_124913884	80.489		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr1_+_110882063	79.930		RBM15	RNA binding motif protein 15
chr12_+_56211862	79.782		ORMDL2	ORM1-like 2 (S. cerevisiae)
chr1_-_153643474	79.459	NM_004515	ILF2	interleukin enhancer binding factor 2, 45kDa
chr1_-_35658731	78.796		SFPQ	splicing factor proline/glutamine-rich
chr15_+_41625152	78.527		NUSAP1	nucleolar and spindle associated protein 1
chr11_+_63953666	78.256		STIP1	stress-induced-phosphoprotein 1
chr6_+_24775154	77.766	NM_001251989 NM_001251990 NM_015895	GMNN	geminin, DNA replication inhibitor
chr9_-_95055913	76.756		IARS	isoleucyl-tRNA synthetase
chr19_-_14247400	75.870	NM_018154	ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr1_+_110882057	75.713		RBM15	RNA binding motif protein 15
chr5_+_68462836	75.467	NM_031966	CCNB1	cyclin B1
chr8_+_11660272	75.257		FDFT1	farnesyl-diphosphate farnesyltransferase 1
chr5_+_145826866	75.129	NM_001040006 NM_006706	TCERG1	transcription elongation regulator 1
chr14_+_52456322	74.090		C14orf166	chromosome 14 open reading frame 166
chr1_+_43148048	73.548	NM_004559	YBX1	Y box binding protein 1
chr9_-_128003615	73.306		HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr7_+_73097897	72.831	NM_001202560 NM_017528	WBSCR22	Williams Beuren syndrome chromosome region 22
chr1_-_225615701	72.027		LBR	lamin B receptor
chr19_+_41256758	71.782	NM_004596	SNRPA	small nuclear ribonucleoprotein polypeptide A
chr8_+_11660207	71.588		FDFT1	farnesyl-diphosphate farnesyltransferase 1
chr1_+_43148098	71.183		YBX1	Y box binding protein 1
chr2_+_27008912	70.855		CENPA	centromere protein A
chr9_-_95055966	70.618	NM_013417	IARS	isoleucyl-tRNA synthetase
chr15_-_64673569	70.522	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr1_-_35658742	70.152	NM_005066	SFPQ	splicing factor proline/glutamine-rich
chr15_-_76603742	69.748		ETFA	electron-transfer-flavoprotein, alpha polypeptide
chr15_-_76603806	69.697	NM_000126 NM_001127716	ETFA	electron-transfer-flavoprotein, alpha polypeptide
chr2_-_61765367	67.883		XPO1	exportin 1 (CRM1 homolog, yeast)
chr19_-_8070468	67.879	NM_001419	ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr8_+_11660179	67.629	NM_004462	FDFT1	farnesyl-diphosphate farnesyltransferase 1
chr14_-_55658205	67.603	NM_001146015 NM_014750	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr2_-_61765345	67.419		XPO1	exportin 1 (CRM1 homolog, yeast)
chr4_-_1713914	66.766	NM_006527	SLBP	stem-loop binding protein
chr12_+_56211718	66.677	NM_014182	ORMDL2	ORM1-like 2 (S. cerevisiae)
chr15_-_76603728	66.662		ETFA	electron-transfer-flavoprotein, alpha polypeptide
chr13_-_31040035	66.461	NM_002128	HMGB1	high mobility group box 1
chr5_+_162864571	65.759	NM_004060 NM_199246	CCNG1	cyclin G1
chr15_-_76603791	65.587		ETFA	electron-transfer-flavoprotein, alpha polypeptide
chr15_-_41624760	65.499	NM_007280	OIP5	Opa interacting protein 5
chr7_+_73097930	64.218		WBSCR22	Williams Beuren syndrome chromosome region 22
chr11_+_63953586	64.118	NM_006819	STIP1	stress-induced-phosphoprotein 1
chr1_+_43148105	63.822		YBX1	Y box binding protein 1
chr21_-_40720938	63.320		HMGN1	high mobility group nucleosome binding domain 1
chr3_+_172468469	63.165		ECT2	epithelial cell transforming sequence 2 oncogene
chr17_-_79818514	63.139	NM_000918	P4HB	prolyl 4-hydroxylase, beta polypeptide
chr1_+_62902325	63.069	NM_003368	USP1	ubiquitin specific peptidase 1
chr6_+_80714321	63.056	NM_001166691 NM_003318	TTK	TTK protein kinase
chr9_-_128003348	62.441		HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr9_-_95055989	62.330	NM_002161	IARS	isoleucyl-tRNA synthetase
chr9_-_95055986	62.315		IARS	isoleucyl-tRNA synthetase
chr1_-_150669499	62.091	NM_018178	GOLPH3L	golgi phosphoprotein 3-like
chr8_+_11660520	61.446		FDFT1	farnesyl-diphosphate farnesyltransferase 1
chr19_-_46195442	61.146	NM_004597 NM_177542	SNRPD2	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
chr21_-_40721010	60.904	NM_004965	HMGN1	high mobility group nucleosome binding domain 1
chr2_+_27008881	60.897	NM_001809 NM_001042426	CENPA	centromere protein A
chr1_+_155278538	60.422	NM_001135822 NM_001242824 NM_001242825 NM_002004	FDPS	farnesyl diphosphate synthase
chr7_+_6048921	60.148		AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr13_+_53029494	60.102	NM_001098525 NM_018204	CKAP2	cytoskeleton associated protein 2
chr17_+_46970128	60.024	NM_001002027 NM_005175	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr1_+_155278727	58.919		FDPS	farnesyl diphosphate synthase
chr13_-_31039966	58.333		HMGB1	high mobility group box 1
chr1_-_28240953	58.282		RPA2	replication protein A2, 32kDa
chrX_+_150151757	58.238	NM_005342	HMGB3	high mobility group box 3
chr17_+_1733313	58.230		RPA1	replication protein A1, 70kDa
chr2_-_96874507	58.193		STARD7	StAR-related lipid transfer (START) domain containing 7
chr14_+_39644360	57.638	NM_002687	PNN	pinin, desmosome associated protein
chr2_-_234763182	57.594	NM_018410	HJURP	Holliday junction recognition protein
chr3_+_37034983	56.433		MLH1	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
chr19_+_41770336	56.359		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr1_+_43148168	56.051		YBX1	Y box binding protein 1
chr17_+_18759611	55.568	NM_001243936 NM_001243942	PRPSAP2	phosphoribosyl pyrophosphate synthetase-associated protein 2
chr17_+_36908999	55.248	NM_002795	PSMB3	proteasome (prosome, macropain) subunit, beta type, 3
chr17_-_8113862	55.035	NM_004217	AURKB	aurora kinase B
chr5_+_159848835	54.702	NM_004219	PTTG1	pituitary tumor-transforming 1
chr1_+_155278677	54.557	NM_001135821	FDPS	farnesyl diphosphate synthase
chr2_-_234763145	54.393		HJURP	Holliday junction recognition protein
chr16_-_84651639	53.997	NM_021149	COTL1	coactosin-like 1 (Dictyostelium)
chr5_+_159848876	53.713		PTTG1	pituitary tumor-transforming 1
chr1_+_181057835	53.412		IER5	immediate early response 5
chr11_-_134093869	53.310		NCAPD3	non-SMC condensin II complex, subunit D3
chr8_+_11660297	53.110		FDFT1	farnesyl-diphosphate farnesyltransferase 1
chr7_+_6048858	53.107	NM_006303	AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr3_+_51422691	53.080	NM_006010	MANF	mesencephalic astrocyte-derived neurotrophic factor
chr5_-_137878915	53.070	NM_004730	ETF1	eukaryotic translation termination factor 1
chr10_+_124913921	53.052		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr20_-_5100443	52.884	NM_182649	PCNA	proliferating cell nuclear antigen
chr19_+_41770349	52.876		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr19_+_45394459	52.837	NM_001128916 NM_001128917 NM_006114	TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)
chr20_-_5107185	52.551	NM_002592	PCNA	proliferating cell nuclear antigen
chr1_+_214776494	52.067	NM_016343	CENPF	centromere protein F, 350/400kDa (mitosin)
chr19_-_2042022	51.916		MKNK2	MAP kinase interacting serine/threonine kinase 2
chrX_-_77150907	51.830	NM_032121	MAGT1	magnesium transporter 1
chr5_+_44808967	51.727	NM_016640	MRPS30	mitochondrial ribosomal protein S30
chr5_+_162887516	51.365	NM_001142556 NM_001142557 NM_012484 NM_012485	HMMR	hyaluronan-mediated motility receptor (RHAMM)
chr3_+_51422716	51.362		MANF	mesencephalic astrocyte-derived neurotrophic factor
chr5_+_151151514	51.208		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_-_137878808	51.139		ETF1	eukaryotic translation termination factor 1
chr11_-_67275549	51.009		CDK2AP2	cyclin-dependent kinase 2 associated protein 2
chr1_-_35658430	50.872		SFPQ	splicing factor proline/glutamine-rich
chr14_+_52456192	50.732	NM_016039	C14orf166	chromosome 14 open reading frame 166
chr11_+_66406189	50.342		RBM4	RNA binding motif protein 4
chr17_-_79980685	50.280	NM_144998	STRA13	stimulated by retinoic acid 13 homolog (mouse)
chr19_+_41770285	49.880		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr7_+_6048902	49.832		AIMP2	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr1_+_43148142	49.788		YBX1	Y box binding protein 1
chr11_-_64545864	49.685		SF1	splicing factor 1
chr2_+_74425689	49.498	NM_006636	MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr6_+_30688144	49.492	NM_178014	TUBB	tubulin, beta class I
chr2_-_96874569	49.251	NM_020151	STARD7	StAR-related lipid transfer (START) domain containing 7
chr18_-_45457145	49.067		SMAD2	SMAD family member 2
chr16_-_84651519	48.731		COTL1	coactosin-like 1 (Dictyostelium)
chr1_-_27816676	48.595	NM_001201404 NM_006990	WASF2	WAS protein family, member 2
chr11_+_67798077	48.384	NM_002496	NDUFS8	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr19_+_3572958	47.874		HMG20B	high mobility group 20B
chr9_-_35103089	47.520		STOML2	stomatin (EPB72)-like 2
chr17_+_66031814	47.486	NM_002266	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr16_-_58663734	46.999		CNOT1	CCR4-NOT transcription complex, subunit 1
chr19_+_41770329	46.815		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr2_-_96873938	46.792		STARD7	StAR-related lipid transfer (START) domain containing 7
chr19_+_3572950	46.678		HMG20B	high mobility group 20B
chr7_-_30544324	46.311	NM_001199815 NM_001199816 NM_001199817 NM_024051	GGCT	gamma-glutamylcyclotransferase
chr10_-_58121019	46.226	NM_001005413 NM_007057 NM_032997	ZWINT	ZW10 interactor
chr1_+_43148187	46.052		YBX1	Y box binding protein 1
chr10_+_124914279	45.931		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr19_+_41770273	45.723		HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr10_-_58121011	45.675		ZWINT	ZW10 interactor
chr16_+_103892	45.602		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr17_+_66031885	45.511		KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr12_+_56618104	45.412	NM_024068	OBFC2B	oligonucleotide/oligosaccharide-binding fold containing 2B
chr17_-_5322982	45.389	NM_002532	NUP88	nucleoporin 88kDa
chr9_-_35103144	45.159	NM_013442	STOML2	stomatin (EPB72)-like 2
chr19_+_3572903	45.041	NM_006339	HMG20B	high mobility group 20B
chr6_+_30688085	45.006		TUBB	tubulin, beta class I
chr17_+_1733263	44.980	NM_002945	RPA1	replication protein A1, 70kDa
chr6_-_42713837	44.812	NM_003192	TBCC	tubulin folding cofactor C
chr1_+_52195458	44.727	NM_148904 NM_148905 NM_148907	OSBPL9	oxysterol binding protein-like 9
chr11_+_17298278	43.945	NM_005013	NUCB2	nucleobindin 2
chr17_+_80416606	43.731		NARF	nuclear prelamin A recognition factor
chr21_-_34852282	43.620	NM_006134	TMEM50B	transmembrane protein 50B
chr11_-_64545933	43.616	NM_001178030	SF1	splicing factor 1
chr19_+_13049413	43.502	NM_004343	CALR	calreticulin
chr16_-_69760354	43.384		NQO1	NAD(P)H dehydrogenase, quinone 1
chr3_-_141868208	43.359	NM_001178138 NM_001178139	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_52195508	43.330		OSBPL9	oxysterol binding protein-like 9
chr19_-_14247267	43.015		ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr15_+_80352018	42.963		ZFAND6	zinc finger, AN1-type domain 6
chr7_-_148725731	42.529		PDIA4	protein disulfide isomerase family A, member 4
chr11_-_46867840	42.430	NM_001008938 NM_014756	CKAP5	cytoskeleton associated protein 5
chr3_+_37034840	42.148	NM_000249	MLH1	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
chr9_-_35103048	42.087		STOML2	stomatin (EPB72)-like 2
chr4_+_166248816	42.043	NM_001017369 NM_006745	MSMO1	methylsterol monooxygenase 1
chr20_+_25388320	42.030	NM_021067	GINS1	GINS complex subunit 1 (Psf1 homolog)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.28	2.00e-37	GO:0009987	cellular process
1.55	8.59e-37	GO:0044237	cellular metabolic process
3.41	2.27e-36	GO:0022403	cell cycle phase
3.53	3.33e-33	GO:0000278	mitotic cell cycle
3.06	6.92e-33	GO:0022402	cell cycle process
2.77	2.04e-32	GO:0007049	cell cycle
1.66	1.81e-30	GO:0044260	cellular macromolecule metabolic process
1.43	1.40e-28	GO:0008152	metabolic process
3.75	2.26e-28	GO:0000279	M phase
1.47	2.04e-27	GO:0044238	primary metabolic process
1.98	6.22e-26	GO:0090304	nucleic acid metabolic process
2.19	8.55e-26	GO:0006996	organelle organization
1.77	1.16e-25	GO:0034641	cellular nitrogen compound metabolic process
1.75	2.61e-25	GO:0006807	nitrogen compound metabolic process
1.83	6.93e-25	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.09	9.06e-24	GO:0000087	M phase of mitotic cell cycle
1.53	1.88e-23	GO:0043170	macromolecule metabolic process
3.65	5.46e-21	GO:0010564	regulation of cell cycle process
1.78	1.10e-20	GO:0071842	cellular component organization at cellular level
1.76	1.33e-20	GO:0071841	cellular component organization or biogenesis at cellular level
3.87	3.21e-20	GO:0000280	nuclear division
3.87	3.21e-20	GO:0007067	mitosis
3.75	2.46e-19	GO:0048285	organelle fission
2.79	1.18e-18	GO:0051276	chromosome organization
1.62	7.61e-18	GO:0016043	cellular component organization
1.74	1.11e-17	GO:0009058	biosynthetic process
3.59	1.34e-17	GO:0051325	interphase
1.60	1.37e-17	GO:0071840	cellular component organization or biogenesis
3.60	2.23e-17	GO:0051329	interphase of mitotic cell cycle
4.06	3.99e-17	GO:0071156	regulation of cell cycle arrest
2.69	4.60e-17	GO:0051726	regulation of cell cycle
3.33	1.03e-16	GO:0051301	cell division
4.07	1.65e-16	GO:0000075	cell cycle checkpoint
1.71	3.76e-15	GO:0044249	cellular biosynthetic process
2.76	4.67e-14	GO:0034621	cellular macromolecular complex subunit organization
2.28	9.75e-14	GO:0043933	macromolecular complex subunit organization
2.57	9.81e-14	GO:0006259	DNA metabolic process
2.27	1.60e-13	GO:0033554	cellular response to stress
4.29	5.44e-13	GO:0071103	DNA conformation change
4.99	9.68e-13	GO:0065004	protein-DNA complex assembly
4.86	9.70e-13	GO:0071824	protein-DNA complex subunit organization
2.96	2.05e-12	GO:0034622	cellular macromolecular complex assembly
4.52	2.14e-12	GO:0006323	DNA packaging
2.34	3.40e-12	GO:0065003	macromolecular complex assembly
1.79	5.26e-12	GO:0009059	macromolecule biosynthetic process
1.78	1.51e-11	GO:0034645	cellular macromolecule biosynthetic process
1.76	1.52e-11	GO:0016070	RNA metabolic process
4.03	6.08e-10	GO:0006333	chromatin assembly or disassembly
1.89	7.26e-10	GO:0044085	cellular component biogenesis
4.67	8.73e-10	GO:0031497	chromatin assembly
2.50	1.18e-09	GO:0006325	chromatin organization
4.76	1.25e-09	GO:0006334	nucleosome assembly
1.56	1.82e-09	GO:0044267	cellular protein metabolic process
3.92	3.20e-09	GO:0006310	DNA recombination
4.44	3.77e-09	GO:0034728	nucleosome organization
4.40	4.99e-09	GO:0007059	chromosome segregation
2.37	5.32e-09	GO:0006974	response to DNA damage stimulus
1.91	5.92e-09	GO:0022607	cellular component assembly
3.63	8.92e-09	GO:0010498	proteasomal protein catabolic process
3.63	8.92e-09	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.65	1.03e-08	GO:0010467	gene expression
7.16	1.13e-08	GO:0016126	sterol biosynthetic process
4.73	2.34e-08	GO:0000236	mitotic prometaphase
2.29	3.08e-08	GO:0016071	mRNA metabolic process
2.91	3.34e-08	GO:0007017	microtubule-based process
7.55	6.18e-08	GO:0006695	cholesterol biosynthetic process
2.61	9.33e-08	GO:0006281	DNA repair
2.03	1.12e-07	GO:0071844	cellular component assembly at cellular level
2.25	1.32e-07	GO:0044265	cellular macromolecule catabolic process
3.59	1.83e-07	GO:0000082	G1/S transition of mitotic cell cycle
2.81	2.06e-07	GO:0007346	regulation of mitotic cell cycle
1.75	2.21e-07	GO:0051641	cellular localization
2.13	2.37e-07	GO:0009057	macromolecule catabolic process
1.60	3.42e-07	GO:0044281	small molecule metabolic process
3.95	4.42e-07	GO:0000086	G2/M transition of mitotic cell cycle
3.19	4.82e-07	GO:0006260	DNA replication
4.45	1.42e-06	GO:0000216	M/G1 transition of mitotic cell cycle
1.74	2.45e-06	GO:0044248	cellular catabolic process
2.03	3.55e-06	GO:0006396	RNA processing
2.55	3.65e-06	GO:0008380	RNA splicing
3.53	3.73e-06	GO:0007093	mitotic cell cycle checkpoint
2.93	6.35e-06	GO:0006457	protein folding
1.46	8.66e-06	GO:0006950	response to stress
1.63	9.32e-06	GO:0009056	catabolic process
1.72	1.20e-05	GO:0051649	establishment of localization in cell
3.19	1.50e-05	GO:0000226	microtubule cytoskeleton organization
2.03	1.52e-05	GO:0071822	protein complex subunit organization
4.10	1.84e-05	GO:0007088	regulation of mitosis
4.10	1.84e-05	GO:0051783	regulation of nuclear division
5.49	2.01e-05	GO:0000819	sister chromatid segregation
3.57	2.05e-05	GO:0051320	S phase
2.82	2.95e-05	GO:0000375	RNA splicing, via transesterification reactions
2.24	4.14e-05	GO:0006091	generation of precursor metabolites and energy
3.50	6.18e-05	GO:0000084	S phase of mitotic cell cycle
1.83	7.65e-05	GO:0046907	intracellular transport
3.97	7.73e-05	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.37	8.49e-05	GO:0019538	protein metabolic process
2.36	1.04e-04	GO:0006511	ubiquitin-dependent protein catabolic process
4.93	1.18e-04	GO:0007051	spindle organization
2.19	1.54e-04	GO:0006397	mRNA processing
2.30	1.62e-04	GO:0051603	proteolysis involved in cellular protein catabolic process
3.55	1.69e-04	GO:0006694	steroid biosynthetic process
2.31	1.93e-04	GO:0019941	modification-dependent protein catabolic process
2.29	2.36e-04	GO:0043632	modification-dependent macromolecule catabolic process
2.25	2.93e-04	GO:0044257	cellular protein catabolic process
2.20	3.57e-04	GO:0030163	protein catabolic process
5.16	4.31e-04	GO:0000070	mitotic sister chromatid segregation
2.65	5.29e-04	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.65	5.29e-04	GO:0000398	nuclear mRNA splicing, via spliceosome
3.21	6.60e-04	GO:0051640	organelle localization
1.42	9.96e-04	GO:0048523	negative regulation of cellular process
10.57	1.29e-03	GO:0000085	G2 phase of mitotic cell cycle
10.57	1.29e-03	GO:0051319	G2 phase
3.19	1.31e-03	GO:0007126	meiosis
3.19	1.31e-03	GO:0051327	M phase of meiotic cell cycle
1.96	1.51e-03	GO:0070271	protein complex biogenesis
3.16	1.56e-03	GO:0051321	meiotic cell cycle
5.93	1.78e-03	GO:0006271	DNA strand elongation involved in DNA replication
1.98	1.90e-03	GO:0006066	alcohol metabolic process
2.00	1.99e-03	GO:0044262	cellular carbohydrate metabolic process
3.02	2.11e-03	GO:0010639	negative regulation of organelle organization
1.94	2.66e-03	GO:0006461	protein complex assembly
3.50	2.82e-03	GO:0051656	establishment of organelle localization
1.37	3.21e-03	GO:0048522	positive regulation of cellular process
5.54	4.02e-03	GO:0022616	DNA strand elongation
1.42	4.04e-03	GO:0043412	macromolecule modification
3.17	4.39e-03	GO:0016125	sterol metabolic process
1.79	5.05e-03	GO:0005975	carbohydrate metabolic process
3.21	6.20e-03	GO:0051340	regulation of ligase activity
1.89	6.63e-03	GO:0007010	cytoskeleton organization
1.17	7.16e-03	GO:0050794	regulation of cellular process
2.74	8.43e-03	GO:0051052	regulation of DNA metabolic process
2.10	8.79e-03	GO:0033043	regulation of organelle organization
1.36	9.19e-03	GO:0048519	negative regulation of biological process
2.94	9.49e-03	GO:0031570	DNA integrity checkpoint
1.15	9.63e-03	GO:0065007	biological regulation
3.66	1.04e-02	GO:0010948	negative regulation of cell cycle process
1.41	1.04e-02	GO:0006464	protein modification process
2.02	1.11e-02	GO:0016568	chromatin modification
5.04	1.18e-02	GO:0051297	centrosome organization
3.32	1.22e-02	GO:0051351	positive regulation of ligase activity
3.19	1.24e-02	GO:0051438	regulation of ubiquitin-protein ligase activity
4.27	1.32e-02	GO:0006458	'de novo' protein folding
1.59	1.34e-02	GO:0032774	RNA biosynthetic process
1.27	1.34e-02	GO:0080090	regulation of primary metabolic process
2.18	1.35e-02	GO:0015980	energy derivation by oxidation of organic compounds
10.07	1.38e-02	GO:0002566	somatic diversification of immune receptors via somatic mutation
10.07	1.38e-02	GO:0016446	somatic hypermutation of immunoglobulin genes
1.27	1.43e-02	GO:0031323	regulation of cellular metabolic process
1.55	1.60e-02	GO:0008104	protein localization
1.25	1.75e-02	GO:0019222	regulation of metabolic process
1.56	1.81e-02	GO:0032268	regulation of cellular protein metabolic process
1.55	1.84e-02	GO:0010941	regulation of cell death
1.56	1.96e-02	GO:0042981	regulation of apoptosis
3.34	2.04e-02	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.74	2.06e-02	GO:0046034	ATP metabolic process
1.28	2.06e-02	GO:0060255	regulation of macromolecule metabolic process
1.15	2.07e-02	GO:0050789	regulation of biological process
3.29	2.46e-02	GO:0051443	positive regulation of ubiquitin-protein ligase activity
3.16	2.47e-02	GO:0018196	peptidyl-asparagine modification
3.16	2.47e-02	GO:0018279	protein N-linked glycosylation via asparagine
1.87	2.56e-02	GO:0008283	cell proliferation
1.53	2.68e-02	GO:0051246	regulation of protein metabolic process
1.59	2.75e-02	GO:0055114	oxidation-reduction process
1.54	2.78e-02	GO:0043067	regulation of programmed cell death
1.50	2.83e-02	GO:0050790	regulation of catalytic activity
5.04	3.20e-02	GO:0071174	mitotic cell cycle spindle checkpoint
3.71	3.47e-02	GO:0000910	cytokinesis
1.47	3.60e-02	GO:0033036	macromolecule localization
2.88	3.62e-02	GO:0090068	positive regulation of cell cycle process
4.49	4.09e-02	GO:0031023	microtubule organizing center organization
2.85	4.19e-02	GO:0000077	DNA damage checkpoint
5.44	4.28e-02	GO:0002200	somatic diversification of immune receptors
1.30	4.54e-02	GO:0048518	positive regulation of biological process
2.82	4.83e-02	GO:0042770	signal transduction in response to DNA damage

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.35	8.51e-66	GO:0044424	intracellular part
1.32	9.25e-62	GO:0005622	intracellular
1.42	4.43e-59	GO:0043226	organelle
1.42	4.81e-59	GO:0043229	intracellular organelle
1.47	1.17e-58	GO:0043227	membrane-bounded organelle
1.47	5.61e-58	GO:0043231	intracellular membrane-bounded organelle
1.72	4.67e-56	GO:0044422	organelle part
1.73	7.15e-56	GO:0044446	intracellular organelle part
1.42	3.22e-40	GO:0005737	cytoplasm
1.60	1.24e-37	GO:0005634	nucleus
1.81	2.56e-35	GO:0032991	macromolecular complex
2.02	1.10e-30	GO:0070013	intracellular organelle lumen
1.99	2.58e-30	GO:0031974	membrane-enclosed lumen
2.02	1.66e-29	GO:0044428	nuclear part
1.98	3.75e-29	GO:0043233	organelle lumen
1.49	7.01e-29	GO:0044444	cytoplasmic part
3.20	2.42e-26	GO:0005694	chromosome
1.99	1.56e-22	GO:0031981	nuclear lumen
1.75	8.77e-22	GO:0043228	non-membrane-bounded organelle
1.75	8.77e-22	GO:0043232	intracellular non-membrane-bounded organelle
3.17	3.90e-21	GO:0044427	chromosomal part
1.70	4.60e-21	GO:0043234	protein complex
1.84	1.95e-19	GO:0005829	cytosol
2.07	6.44e-18	GO:0005654	nucleoplasm
1.09	1.35e-14	GO:0044464	cell part
1.09	1.42e-14	GO:0005623	cell
2.38	9.73e-14	GO:0015630	microtubule cytoskeleton
2.22	1.81e-11	GO:0031967	organelle envelope
2.18	5.56e-11	GO:0031975	envelope
3.55	1.34e-10	GO:0005819	spindle
3.15	2.95e-10	GO:0000785	chromatin
3.80	1.45e-09	GO:0000793	condensed chromosome
3.47	2.00e-09	GO:0044454	nuclear chromosome part
2.32	2.29e-09	GO:0030529	ribonucleoprotein complex
3.17	2.35e-09	GO:0000228	nuclear chromosome
2.11	4.11e-09	GO:0044429	mitochondrial part
4.29	2.14e-08	GO:0032993	protein-DNA complex
3.51	6.10e-08	GO:0000775	chromosome, centromeric region
1.69	1.21e-07	GO:0005739	mitochondrion
2.20	7.91e-07	GO:0005740	mitochondrial envelope
1.50	8.40e-07	GO:0031090	organelle membrane
4.78	2.13e-06	GO:0000786	nucleosome
3.95	3.42e-06	GO:0000776	kinetochore
3.92	3.60e-05	GO:0000779	condensed chromosome, centromeric region
1.65	4.46e-05	GO:0044430	cytoskeletal part
2.55	4.99e-05	GO:0005813	centrosome
3.99	5.74e-05	GO:0000777	condensed chromosome kinetochore
2.33	7.25e-05	GO:0005874	microtubule
2.05	7.68e-05	GO:0031966	mitochondrial membrane
1.78	1.14e-04	GO:0044451	nucleoplasm part
1.74	2.35e-04	GO:0044432	endoplasmic reticulum part
1.47	3.79e-04	GO:0012505	endomembrane system
2.10	7.50e-04	GO:0005815	microtubule organizing center
4.12	7.57e-04	GO:0000794	condensed nuclear chromosome
2.09	8.16e-04	GO:0019866	organelle inner membrane
1.46	9.98e-04	GO:0005856	cytoskeleton
2.24	1.39e-03	GO:0005759	mitochondrial matrix
3.66	1.88e-03	GO:0000922	spindle pole
3.84	1.98e-03	GO:0030496	midbody
2.08	2.71e-03	GO:0005743	mitochondrial inner membrane
6.71	3.67e-03	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
2.19	5.65e-03	GO:0005635	nuclear envelope
3.06	7.38e-03	GO:0042470	melanosome
3.06	7.38e-03	GO:0048770	pigment granule
1.65	7.72e-03	GO:0042175	nuclear membrane-endoplasmic reticulum network
2.90	9.51e-03	GO:0005788	endoplasmic reticulum lumen
1.64	1.20e-02	GO:0005789	endoplasmic reticulum membrane
8.24	1.22e-02	GO:0000780	condensed nuclear chromosome, centromeric region
1.48	1.61e-02	GO:0005783	endoplasmic reticulum
9.44	2.54e-02	GO:0042555	MCM complex
1.71	3.33e-02	GO:0005730	nucleolus
2.07	4.96e-02	GO:0016604	nuclear body

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.45	8.02e-34	GO:0005515	protein binding
1.20	4.59e-23	GO:0005488	binding
1.92	1.03e-07	GO:0003723	RNA binding
1.38	9.07e-07	GO:0003676	nucleic acid binding
1.23	7.54e-05	GO:0003824	catalytic activity
1.41	8.75e-05	GO:0000166	nucleotide binding
1.77	1.24e-04	GO:0019899	enzyme binding
4.24	3.11e-04	GO:0003697	single-stranded DNA binding
2.53	8.69e-04	GO:0043566	structure-specific DNA binding
1.67	1.26e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
2.83	1.77e-03	GO:0016853	isomerase activity
1.45	1.82e-03	GO:0030554	adenyl nucleotide binding
1.66	2.00e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.45	2.46e-03	GO:0005524	ATP binding
2.44	2.85e-03	GO:0003682	chromatin binding
1.65	3.14e-03	GO:0016462	pyrophosphatase activity
1.44	3.45e-03	GO:0032559	adenyl ribonucleotide binding
2.69	4.63e-03	GO:0003690	double-stranded DNA binding
1.65	4.83e-03	GO:0017111	nucleoside-triphosphatase activity
1.33	9.63e-03	GO:0003677	DNA binding
4.15	2.32e-02	GO:0003678	DNA helicase activity
3.36	2.93e-02	GO:0008094	DNA-dependent ATPase activity
1.89	3.02e-02	GO:0016887	ATPase activity
1.33	4.14e-02	GO:0017076	purine nucleotide binding
1.34	4.24e-02	GO:0035639	purine ribonucleoside triphosphate binding
3.86	4.81e-02	GO:0042826	histone deacetylase binding